The NCBI is directed by David Lipman, one of the original authors of the BLAST sequence alignment program and a widely respected figure in Bioinformatics. He also leads an intramural research program, including groups led by Stephen Altschul (another BLAST co-author), David Landsman, and Eugene Koonin (a prolific author on comparative genomics).
GenBank
main|GenBankThe NCBI has had responsibility for making available the GenBank DNA sequence database since 1992. GenBank coordinates with individual laboratories and other sequence databases such as those of the European Molecular Biology Laboratory (EMBL) and the DNA Database of Japan (DDBJ).
Since 1992, NCBI has grown to provide other databases in addition to GenBank. NCBI provides Online Mendelian Inheritance in Man, the Molecular Modeling Database (3D protein structures), the Unique Human Gene Sequence Collection, a Gene Map of the Human genome, a Taxonomy Browser, and coordinates with the National Cancer Institute to provide the Cancer Genome Anatomy Project. The NCBI assigns a unique identifier (Taxonomy ID number) to each species of organism.
The NCBI has software tools that are available by WWW browsing or by FTP. For example, BLAST is a sequence similarity searching program. BLAST can do sequence comparisons against the GenBank DNA database in less than 15 seconds.
NCBI Bookshelf
The NCBI Bookshelf is a collection of freely available, on-line versions of selected biomedical books. As of March 2006, the Bookshelf had 55 titles covering aspects of molecular biology, biochemistry, cell biology, genetics, microbiology, a couple of disease states from a molecular and cellular point of view, research methods, and virology. Some of the books are online versions of previously published books, while others, such as Coffee Break , are written and edited by NCBI staff. The Bookshelf is a complement to the Entrez PubMed repository of peer-reviewed publication abstracts in that Bookshelf contents provide established perspectives on evolving areas of study and a context in which many disparate individual pieces of reported research can be organized. -->Ayrıca bakınız
- National Institutes of Health
- United States National Library of Medicine
- Medline
- Entrez
- PubMed
- GenBank
Dış bağlantarı
- National Center for Biotechnology Information sitesi
- mGen containing four of the world`s biggest databases - GenBank, Refseq, EMBL and DDBJ - easy and simple program with friendly gene extraction.
- Genomdiff - Open Source Java Program to make a dotplot from online genomes
- - NCBI Education homepage
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